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Description:This article is distributed under the terms of the Creative Commons Attribution License CC-BY , which permits unrestricted use and redistribution provided that the original author and source are credited. This article has been cited by other articles in PMC. The aim of the study is to identify key signaling pathways that control metastasis in ESCC. Highly invasive ESCC sublines designated I3 cells were established through three rounds of selection of cancer cells invading through matrigel-coated chambers.

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